The connection between gut health and immune resilience is a topic that’s gaining plenty of attention, as more research reveals just how closely intertwined these systems are. Our gut microbiome, composed of trillions (yes, trillions!) of bacteria, is crucial in supporting our immune defenses.  

But how exactly does our digestive system's health impact how our body fights off illness?  We asked two renowned gut health experts, Dr. Tom O’Bryan and Sheri Vettel, RD. 

According to Dr. O’Bryan, a leading expert in integrative medicine, "The gut houses nearly 70% of the immune system, making it the cornerstone of overall health. A well-balanced microbiome can help prevent harmful invaders from entering the bloodstream and triggering immune responses." 

Vettel emphasizes the importance of stress in this equation. “A few key factors for maintaining a healthy balance of microbes in the gut are shifting one’s perception of stress and soothing high stress levels,” Sheri tells us. “It’s important to get quality sleep, choose a variety of plant-based foods that are rich in fiber, polyphenols, prebiotics, and probiotics, and exercise.”  

Understanding the Gut-Immune System Axis

At the core of this connection is the gut-immune system axis, an intricate communication pathway between the gut microbiota and immune cells. When the gut is healthy, it works to regulate immune activity, prevent inflammation, and maintain balance. However, when gut health is compromised — through poor diet, stress, or lack of sleep — it can weaken the immune system, leaving the body more vulnerable to infections. 

"An imbalance in the microbiome can lead to chronic inflammation, which is a precursor to many immune-related diseases," says Dr. O’Bryan. "By improving gut health, we can reduce the risk of these conditions and promote long-term wellness." 

Strategies to Support Gut Health and Immunity

To keep your gut and immune system thriving, experts recommend learning more about your bio-individuality.  

As Vettel emphasizes, “While there are universal wellness practices that support a healthier gut, bio-individuality plays a crucial role in identifying what will support your own gut and overall health the most. One powerful way to achieve this is by truly listening to your gut. The signals it sends — whether through food sensitivities, gas, bloating, pain, or other discomforts — are your body’s way of communicating its needs. Ignoring these cues can prevent you from providing the care necessary for your body to heal and thrive.” 

Another just-as-important strategy is to incorporate gut-friendly foods such as fermented vegetables, yogurt with live cultures, and fiber-rich plants into your diet. As Dr. O’Bryan succinctly puts it, “Many people address inflammation with medication, but what they don’t realize is that food is medicine.”  

Probiotic and prebiotic-rich foods are key to fostering a diverse and balanced microbiome. They not only enhance digestion, but also play a crucial role in modulating the immune response.  

By focusing on these strategies, you can unlock the powerful connection between your gut and your immune system, laying the foundation for better health and vitality. 

Maintain a Healthy Gut with IIN 

If you’re ready to dive deeper into the gut-immune system connection, we have some incredible resources for you. Both the Health Coach Training Program and the Gut Health Course provide you with the knowledge and tools to understand how gut health influences not just your immune system, but your overall well-being.  

Through expert insights, practical tips, and actionable strategies, you’ll learn how to support a thriving microbiome and unlock the full potential of your health.  

Want to explore the course for yourself before enrolling? Try our Health Coach Training Program Sample Class today and experience what it’s like to be a student!